In 1517 the Spanish conquistadors, led by Hernán Cortés, arrived in Tenochtitlan, the capital of the Aztec Empire. The ruler of the Aztecs, Motecuhzoma II, made the Spanish welcome and things were friendly between the Spanish and the Aztecs initially. Two years later the conquistadors began their conquest of Mexico, and by August 1521 Tenochtitlan … Continue reading Smallpox and the Conquest of Mexico